Source: University of Maryland
A new study reveals
that racism may impact aging at the cellular level. Researchers found signs of
accelerated aging in African American men, ages reporting high levels of racial
discrimination and who had internalized anti-Black attitudes. Findings from the
study, which is the first to link racism-related factors and biological aging,
are published in the American Journal of Preventive Medicine.
Racial disparities in
health are well-documented, with African Americans having shorter life
expectancy, and a greater likelihood of suffering from aging-related illnesses
at younger ages compared to Whites. Accelerated aging at the biological level
may be one mechanism linking racism and disease risk.
"We examined a
biomarker of systemic aging, known as leukocyte telomere length,"
explained Dr. David H. Chae, assistant professor of epidemiology at the
University of Maryland School of Public Health and the study's lead
investigator.
Shorter telomere length is associated with increased risk of
premature death and chronic disease such as diabetes, dementia, stroke and
heart disease. "We found that the African American men who experienced
greater racial discrimination and who displayed a stronger bias against their
own racial group had the shortest telomeres of those studied."
Telomeres are
repetitive sequences of DNA capping the ends of chromosomes, which shorten
progressively over time -- at a rate of approximately 50-100 base pairs
annually. Telomere length is variable, shortening more rapidly under conditions
of high psychosocial and physiological stress.
"Telomere length may be a
better indicator of biological age, which can give us insight into variations
in the cumulative 'wear and tear' of the organism net of chronological
age," said Chae. Among African American men with stronger anti-Black
attitudes, investigators found that average telomere length was 140 base pairs
shorter in those reporting high vs. low levels of racial discrimination; this
difference may equate to 1.4 to 2.8 years chronologically.
Participants in the
study were 92 African American men between 30-50 years of age. Investigators
asked them about their experiences of discrimination in different domains,
including work and housing, as well as in getting service at stores or
restaurants, from the police, and in other public settings. They also measured
racial bias using the Black-White Implicit Association Test. This test gauges
unconscious attitudes and beliefs about race groups that people may be unaware
of or unwilling to report.
Even after adjusting for
participants' chronological age, socioeconomic factors, and health-related
characteristics, investigators found that the combination of high racial
discrimination and anti-Black bias was associated with the shortest telomeres.
On the other hand, the data revealed that racial discrimination had little
relationship with telomere length among those holding pro-Black attitudes.
"African American men who have more positive views of their racial group
may be buffered from the negative impact of racial discrimination,"
explained Chae. "In contrast, those who have internalized an anti-Black
bias may be less able to cope with racist experiences, which may result in
greater stress and shorter telomeres."
The findings from
this study are timely in light of regular media reports of racism facing
African American men. "Stop-and-frisk policies, and other forms of
criminal profiling such as 'driving or shopping while Black' are inherently
stressful and have a real impact on the health of African Americans," said
Chae.
Researchers found that racial discrimination by police was most commonly
reported by participants in the study, followed by discrimination in
employment. In addition, African American men are more routinely treated with
less courtesy or respect, and experience other daily hassles related to racism.
Chae indicated the
need for additional research to replicate findings, including larger studies
that follow participants over time. "Despite the limitations of our study,
we contribute to a growing body of research showing that social toxins
disproportionately impacting African American men are harmful to health,"
Chae explained. "Our findings suggest that racism literally makes people
old."
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